Friday, September 24, 2021

Coronavirus, the Late September Edition

 Coronavirus, the Late September Edition

By the Numbers
The Numbers 
Nationwide, the numbers continue to oscillate around 3 million active cases. Almost all the states are in decline,
Sending the kids to school seems to be a major factor. In Pennsylvania, 30% of the new cases, some 20,000 of the 70,000 new cases in the last two weeks, are school age children.
San Francisco seems to be doing a good job on tracking sources of infection, and identified that the vast majority of school age infections were acquired in the home, not at the school.
Booster shots
The information on booster shots changes daily. Currently the CDC is recommending booster shots for "at risk" people whose last vaccination was 8 months ago. The reported decline in efficacy of the vaccines is still wildly varied. But even the lowest numbers, about 65%, are above what immunologists would consider effective. 
Ethicists are complaining, and rightly so, if Americans don't want the vaccine, then ship it to locations around the world that need it. Let none go to waste. The logistics of shipping the mRNA virus is daunting as they require a very cold environment, but doable. It would be a great photo op to have thousands of Nigerians lining up at the air plane for their shots. We could tell the Refusenicks the Nigerians are getting their shots. 
Refusenick Hell
I have tried to avoid talking about the death counts in my missives. My goal is not to induce fear, but provide context through the numbers. But sometimes, the death count is what is required to make the point. 
How badly is the current Covid surge affecting the refuseniks of the vaccine? At the peak of the pandemic, the 15 weeks from November 2020 to February 2021, 286,000 Americans died of Covid out of an adult population of 255 million*, or about 1,122 out of every million. 
During the 15 weeks from June to September 11, 75,000 died of Covid. The CDC places this loss as 85% unvaccinated so the number of the unvaccinated that have died is 63,900. Every hospital graph I have seen puts this at 95%+**, and I have seen dozens of them by now, but I have to assume the CDC did a better job of looking at all hospitals, and not just the ones promoting their beds dedicated to Covid. So I'll use their lower number.
The number of unvaccinated adults from June-Sept is around 97 million. This puts the death count per million at 736 per million. In the same time frame the death count for the vaccinated is 71 per million. 
And this does not consider the long term debilitating effects of the virus settling into your vascular system. This seems to effect about 32% of all the moderate to serious cases of Covid. Assuming the serious cases are all hospitalized and that number is closed to 3 million, almost 700,000 died, giving us around 730,000 with various "Long Hauler" effects.
So it is the concentration of Covid that is the major problem. This is nothing we didn't already know. But even in those areas, Covid is not spreading as badly as it did at it's peak last winter. Even in the refusenik strongholds about 40% are vaccinated, and that seems to have mitigated the disaster that has fallen on them. It's just those areas tend to be much poorer and less able to deal with a reduced version of this plague. 
*I know children are catching Delta now, but they are still a small percentage of the serious cases. Feel free to distort my numbers a couple of percentage points to account for them.
**DC reports their breakthrough rate at .72%, PA at 6%, NJ at .002%. A very wide range.
Which States are still growing, and which are declining.
The graph below is the counts of NEW cases for each state and protectorate for the last 4 weeks. 
2 states and the Navajo nation are still showing an increase from last week. the rest are reporting a decline. 10 have a less than 10% decline, the rest more so.
27 states and protectorates still have more new cases this week than 4 weeks ago.
Looks like my prediction of a sharp drop in September was bogus. 
State 8/25 to 8/31 9/1 to 9/7 9/8 to 9/14 9/15 to 9/21 4 weeks change Last week change
Alabama 7,805 11,695 11,765 6,923 89% 59%
Alaska 2,499 3,039 4,679 4,307 172% 92%
Arizona 22,387 21,730 21,129 16,919 76% 80%
Arkansas 14,023 15,050 13,795 9,191 66% 67%
California 82,920 85,150 74,143 54,379 66% 73%
Colorado 8,271 12,020 12,492 8,672 105% 69%
Connecticut 4,659 3,872 4,985 5,418 116% 109%
Delaware 2,159 3,098 3,332 3,245 150% 97%
DistrictOfColumbia 1,355 991 1,871 1,402 103% 75%
FederalPrisons 7,797 7,703 7,991 5,417 69% 68%
Florida 130,389 86,716 82,082 49,333 38% 60%
Georgia 47,404 47,389 48,877 27,390 58% 56%
Guam 5,483 4,231 3,012 2,010 37% 67%
Hawaii 6,279 5,815 4,504 3,246 52% 72%
Idaho 5,189 6,406 10,222 7,888 152% 77%
Illinois 18,818 22,841 27,389 15,963 85% 58%
Indiana 21,067 21,312 27,941 17,022 81% 61%
Iowa 559 1,918 734 437 78% 60%
Kansas 4,534 4,074 7,051 5,314 117% 75%
Kentucky 22,206 22,319 29,798 20,077 90% 67%
Louisiana 18,992 8,583 17,813 8,597 45% 48%
Maine 1,722 2,690 3,884 3,264 190% 84%
MarianaIslands 867 1,000 1,402 944 109% 67%
Maryland 8,031 8,932 9,073 8,621 107% 95%
Massachusetts 8,075 8,912 13,665 9,248 115% 68%
Michigan 6,754 7,037 13,710 13,280 197% 97%
Minnesota 10,872 10,361 15,867 15,686 144% 99%
Mississippi 16,799 13,883 15,150 10,555 63% 70%
Missouri 16,802 16,625 18,936 13,934 83% 74%
Montana 3,374 3,758 6,684 6,552 194% 98%
NavajoNation 142 151 109 127 89% 117%
Nebraska 3,934 3,117 4,607 3,244 82% 70%
Nevada 5,726 6,036 8,487 5,534 97% 65%
NewHampshire 1,436 1,239 2,465 1,580 110% 64%
NewJersey 13,908 14,955 18,571 15,419 111% 83%
NewMexico 4,303 4,230 4,604 3,143 73% 68%
NewYork 29,912 36,878 42,310 37,892 127% 90%
NorthCarolina 32,047 33,214 41,509 29,736 93% 72%
NorthDakota 2,062 2,986 4,084 3,153 153% 77%
Ohio 31,225 47,032 57,247 46,633 149% 81%
Oklahoma 17,280 12,660 16,764 9,952 58% 59%
Oregon 11,945 11,119 13,790 8,858 74% 64%
Pennsylvania 22,757 27,602 34,542 32,415 142% 94%
PuertoRico 210 223 248 248 118% 100%
RhodeIsland 1,557 1,509 2,543 1,843 118% 72%
SouthCarolina 22,981 25,450 30,040 17,973 78% 60%
SouthDakota 2,613 2,389 2,969 2,385 91% 80%
Tennessee 25,980 42,424 42,194 19,165 74% 45%
Texas 104,973 121,365 141,900 79,116 75% 56%
USATotalNotincludedintotals 909,368 941,555 1,090,958 753,411 83% 69%
USMilitary 2,572 2,183 4,540 2,001 78% 44%
Utah 6,103 6,931 11,428 7,448 122% 65%
Vermont 912 1,281 1,259 1,391 153% 110%
Virginia 19,319 23,199 29,887 21,523 111% 72%
Washington 17,676 18,907 24,838 14,822 84% 60%
WestVirginia 5,787 10,007 14,676 12,707 220% 87%
Wisconsin 10,478 11,778 16,640 16,339 156% 98%
Wyoming 3,194 3,095 4,402 3,266 102% 74%

Friday, September 10, 2021

Coronavirus, the Early September Edition

Coronavirus, the Early September Edition

By the Numbers

The Numbers 
Nationwide, we seem to have hit peak, and the number of new cases is now in a slight decline.  The last 4 days are showing about 2% fewer new cases than the week before.  The estimated total of active cases is over 3 million.  However, there is a 3 day holiday in the totals, and that tends to reduce the number of cases as it screws up the reporting.  But even the Thursday number, 160,748, is less than last Thursdays of 182,593.  So the decline seems real.

Nationwide, the estimated number of active cases continues to hold at just above 3 million.  Where it has been since 9/1/2021. 

Why is no one is dying of Covid in Florida anymore?
Florida changed how they report Covid death counts.  From the date the death certificate is processed, to the date of the actual death.  Because of this, if you were to graph Florida's deaths, it will now always look liked it peaked a few days back, and is now in decline.  When in fact, with Florida, the number of deaths is increasing commensurate with their disproportionate number of active cases.  Florida has 16% the number of cases in the nation, apportioned to 6.5% of the population.

But there is another subtle change in the day to day statistics.  If you look at Florida's numbers today, or yesterday, there are zero deaths.  So someone looking at the charts would think Florida is doing a good job as no one has died.  Their count of total deaths continues to go up, it is just not graphed.  See this web site.
 
An example Wednesdays numbers vs Thursdays.  Florida logged in 9 new deaths, but their total deaths went from 46,942 to  48,273.  +1,331!

Mu
The variant known as Mu, mutated in existence in Columbia, where it is the dominant variant.  The press is saying much about Mu, while knowing very little.  I have notice the word "could" used a lot.  Could be vaccine evading, could be more infectious.   The short answer is We... Don't... Know...

First on vaccine evasion.  This is just a fear mongering press trying to get head lines.  We... Don't... Know...  Mu mutated in Columbia in Jan, 2021, so it is impossible that it mutated in response to the current vaccines.

Mu has been identified in every state save Nebraska.  In each area, it represents less than 1% of the total cases.  Far less.  For example, in California, 380 cases have been identified, as opposed to an estimated 254,000 active cases, or .15% the total.

My thoughts are that if Mu was more infectious/deadlier/vaccine evading, it would be more prominent than that.    With a press corps tired of reporting about Covid, this is just something new to write up.

An example from the NY Daily News on press prevarication, "The U.S. saw its peak of Mu variant cases in mid-July but case numbers involving that variant have been declining since, signaling either a weakening of the strain or indicating a worrisome future."

Ivermectin 
The anti-parasitic drug Ivermectin has captured the imagination of meme developers everywhere.  Here is what we know.  Ivermectin and HCQ have both been looked into extensively as a treatment for Covid.  Both have been suggested in looking for a reason the Covid has not cut a swath through equatorial Africa.  Both drugs are in heavy use there for treating the various parasites in that region.

Ivermectin's supporters claim it has not been studied, and allude to pharmaceutical company conspiracies.  Anti-vaxers have latched onto it as an alternative to vaccines.
 
It has been studied.  At least 57 studies so far.  And only one study has shown efficacy.  The rest have not. 
 
The one study has been heavily downloaded and shared on the anti-vax boards.  The study as it was originally published, was not peer reviewed.  But that is part of the normal process.  We have a month or so now of medical researchers looking at the paper, and they have issues with methodology and record keeping.  Notably duplicate patient numbers and incomplete records of patients that showed positive effects vice those that did not.
 
The American Journal of Therapeutics, where they looked at many of these studies and posted their results here.   In their final evaluation, with the exception of just one category, all the "quality of evidence" ratings of these studies is rated "low" or "very low".  However, that one category is "death from any cause".  78 out of 1,000 for no ivermectin verses 48 per 1,000 for ivermectin.  A 61% improvement in death from any cause. So the Journal's conclusion reads:
 
"Moderate-certainty evidence finds that large reductions in COVID-19 deaths are possible using ivermectin. Using ivermectin early in the clinical course may reduce numbers progressing to severe disease. The apparent safety and low cost suggest that ivermectin is likely to have a significant impact on the SARS-CoV-2 pandemic globally."

Unfortunately, this has been taken to heart by the anti-vax refusenicks as meaning they do not need the vaccine. They are only told ivermectin is an effective treatment, and can be used as preventive medicine.  
 
And many are raiding veterinary supplies for non prescription ivermectin.  Unfortunately the recommended dosage's are in mcg per kg of the patient.  You know, metric, and you have to do math.  And it comes in pills and liquid.  People are getting it wrong and adding to the ER load.

Where the logic falls down is 61% improvement on outcomes with ivermectin is not as good as 17-1 (94.2%) benefit of the vaccine is currently (CDC Aug 13) showing at preventing hospitalizations, this number has Delta factored in, but may not be weighted properly, but I'll go with the experts.  If you want ivermectin after you get hospitalized, I have no problem with that, but also be aware, it is not just ivermectin, but there is no established treatment regimen yet in this country, or any western country.

Where there is a treatment regimen is in Brazil.  A cocktail of ivermectin, HCQ, anti-inflammatory drugs,  tetracycline, azithromycin, referred to as "early treatment". So we have a real world experiment on the value of this drug.  Brazil has a population 2/3rd's the US, and 584,000 deaths compared to the US's 666,000.

It's not an either or thing with ivermectin, except for the anti-vax refusenicks.  They have signs up declaring "We have ivermectin, you can keep your vaccine." 
 
States in decline
I missed this last surge was going to happen.  During all of June, the numbers averaged 11,600 new cases daily.  Down from a peak of 301,000 on Jan 8.   I was lulled into a sense that Covid was over.  The vaccine had won, and we could go about our lives.  I was contemplating the final edition of this missive.
 
Evidence of this surge was there in the numbers, and I missed it. The clue was the stabilization.  Which implies the bottom of the curve, when it should have continued to decline.  When you bottom out, you can only go up.  I didn't catch that, while some  states were in decline, others were increasing.  Concentrating in the Covid denial areas and growing.  
 
As of today, we do have the reverse situation happening.  Most states are in decline.  This is the list where Covid is still climbing:
Iowa            1,613 new cases last week, a 283% increase over the previous week.
Louisiana    11,977 new cases last week, a 150% increase over the previous week.
West Virginia 8,975 new cases last week, a 136% increase over the previous week.
--------------------------------------------------------------------------------------------------
These states are still increasing but between 101 and 113% of the previous week.
Maine
Nebraska
Ohio
North Dakota
Puerto Rico
Pennsylvania
New York


The rest of the states, protectorates, military, and districts are in decline.
 
Though, Florida is in doubt, as their change in counting makes it seem like they are in serious decline, at 44% the previous week, but that is just statistical bull shit.